Tirzepatide 10mg
$39.99
Tirzepatide | 10mg | Research Peptide
What is Tirzepatide?
Tirzepatide is a novel synthetic dual-agonist peptide consisting of 39 amino acids, designed to simultaneously activate both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors. This dual mechanism of action distinguishes tirzepatide from single-agonist GLP-1 receptor agonists and represents a significant advancement in the study of incretin-based metabolic research. The peptide is based on the native GIP sequence and incorporates structural modifications — including a C20 fatty diacid moiety attached via a gamma-glutamic acid linker — that confer enhanced receptor binding affinity and an extended pharmacological half-life.
The simultaneous engagement of both GIP and GLP-1 receptors creates a synergistic effect on downstream metabolic signaling pathways that neither receptor agonist produces independently. GIP receptors are expressed broadly across adipose tissue, bone, and the central nervous system, while GLP-1 receptors are concentrated in pancreatic tissue, the hypothalamus, and the cardiovascular system. Tirzepatide's ability to engage both receptor systems simultaneously has made it one of the most extensively researched dual-incretin compounds in contemporary metabolic and endocrinological research. Preclinical and clinical studies have investigated its effects across glucose homeostasis, body composition, lipid metabolism, and cardiovascular function.
Overview
Tirzepatide is a first-in-class dual GIP/GLP-1 receptor agonist that has generated significant research interest across metabolic biology, endocrinology, obesity research, and cardiovascular science. Its unique dual-receptor mechanism provides researchers with a powerful tool for investigating the complementary and synergistic roles of GIP and GLP-1 signaling in metabolic regulation, energy homeostasis, and disease pathology.
Product Details
Compound: Tirzepatide
Type: Dual GIP/GLP-1 Receptor Agonist / Synthetic Peptide
Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
Molecular Weight: 4813.48 g/mol
CAS Number: 2023788-19-2
Quantity: 10mg
Appearance: Lyophilized white powder
Purity: ≥99% (HPLC verified)
Reconstitution Fluid: Bacteriostatic Water (BW) or Sterile Saline (0.9% NaCl)
Storage: Store lyophilized peptide at -20°C. Upon reconstitution, store at 4°C and use within 30 days. Do not freeze reconstituted solution. Protect from light.
Research Applications
Tirzepatide has been extensively studied in preclinical and clinical models for its potential roles in:
Dual Incretin Receptor Research — Investigated for its simultaneous activation of GIP and GLP-1 receptors and the synergistic downstream effects on insulin secretion, glucagon suppression, and metabolic signaling.
Metabolic & Glucose Regulation Research — Studied for its glucose-dependent insulinotropic effects on pancreatic beta cells and its role in improving insulin sensitivity in peripheral tissue models.
Obesity & Body Composition Studies — Preclinical and clinical research has explored tirzepatide's capacity to reduce body weight and fat mass through both central appetite suppression and peripheral metabolic modulation, with results exceeding those observed with single GLP-1 agonists.
Lipid Metabolism Research — Investigated for its effects on triglyceride levels, hepatic lipid accumulation, and overall dyslipidemia in animal and clinical models.
Cardiovascular Research — Studied for potential cardioprotective properties including effects on blood pressure, arterial inflammation, and cardiac function in metabolic disease models.
Adipose Tissue Biology — Research has examined tirzepatide's influence on GIP receptor signaling in adipose tissue, including its role in lipid storage, adipokine secretion, and fat cell differentiation.
Non-Alcoholic Fatty Liver Disease (NAFLD) Research — Preclinical models have explored tirzepatide's potential to reduce hepatic steatosis and liver enzyme markers associated with metabolic liver disease.
Research Notes
Tirzepatide is a research compound intended strictly for laboratory and in vitro/in vivo research use only. It is not approved for unsupervised human use outside of licensed medical and clinical settings. All data and findings referenced are sourced from peer-reviewed preclinical and clinical studies.
Handling & Reconstitution (For Research Use)
For research purposes, tirzepatide lyophilized powder is typically reconstituted using bacteriostatic water or sterile saline. Add reconstitution fluid slowly by directing it to the side of the vial and swirling gently — do not shake. Handle under sterile conditions and avoid repeated freeze-thaw cycles to maintain peptide integrity and potency. Protect reconstituted solution from direct light exposure.
Disclaimer
This product is sold for research and laboratory use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. Must be handled by qualified researchers in accordance with all applicable laws and regulations.