Semaglutide 10mg
$44.99
Semaglutide | 10mg | Research Peptide
What is Semaglutide?
Semaglutide is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist consisting of 31 amino acids, structurally analogous to the naturally occurring human GLP-1 hormone. It shares approximately 94% sequence homology with endogenous GLP-1 but has been modified with a C18 fatty acid chain attached via a linker to lysine at position 26, as well as two additional amino acid substitutions. These structural modifications significantly extend its half-life compared to native GLP-1, which degrades rapidly in vivo via dipeptidyl peptidase-4 (DPP-4) enzyme activity.
Originally developed and studied in the context of type 2 diabetes and metabolic disease, semaglutide has become one of the most widely researched GLP-1 receptor agonists in modern pharmacology. Preclinical and clinical research has investigated its mechanisms of action across a broad range of biological systems, including pancreatic beta cell function, hypothalamic appetite regulation, cardiovascular tissue, and hepatic metabolism. Its extended half-life and receptor selectivity have made it a particularly valuable compound for long-duration research protocols.
Overview
Semaglutide is a long-acting GLP-1 receptor agonist that has generated significant interest across multiple research disciplines including metabolic biology, endocrinology, cardiovascular research, and neuroscience. As a research compound, semaglutide provides investigators with a stable, highly selective tool for studying GLP-1 receptor signaling pathways and their downstream effects on glucose homeostasis, appetite regulation, and metabolic function.
Product Details
Compound: Semaglutide
Type: GLP-1 Receptor Agonist / Synthetic Peptide
Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight: 4113.58 g/mol
CAS Number: 910463-68-2
Quantity: 10mg
Appearance: Lyophilized white powder
Purity: ≥99% (HPLC verified)
Reconstitution Fluid: Bacteriostatic Water (BW) or Sterile Saline (0.9% NaCl)
Storage: Store lyophilized peptide at -20°C. Upon reconstitution, store at 4°C and use within 30 days. Do not freeze reconstituted solution. Protect from light.
Research Applications
Semaglutide has been extensively studied in preclinical and clinical models for its potential roles in:
Metabolic & Glucose Regulation Research — Investigated for its role in stimulating insulin secretion in a glucose-dependent manner and suppressing glucagon release in pancreatic tissue models.
Obesity & Body Composition Studies — Preclinical and clinical research has explored semaglutide's ability to reduce food intake and body weight through hypothalamic appetite signaling pathways.
Cardiovascular Research — Studied for its potential cardioprotective effects, including reductions in major adverse cardiovascular events in clinical research models.
Hepatic Metabolism Research — Research has examined semaglutide's influence on non-alcoholic fatty liver disease (NAFLD) and hepatic lipid accumulation in animal models.
Neurological & Neuroprotective Studies — Emerging preclinical research has explored GLP-1 receptor expression in the brain and semaglutide's potential influence on neuroinflammation and neurodegenerative pathways.
Beta Cell Function Research — Studied for its effects on pancreatic beta cell proliferation, preservation, and insulin biosynthesis in in vitro and in vivo models.
Research Notes
Semaglutide is a research compound intended strictly for laboratory and in vitro/in vivo research use only. It is not approved for unsupervised human use outside of licensed medical and clinical settings. All data and findings referenced are sourced from peer-reviewed preclinical and clinical studies.
Handling & Reconstitution (For Research Use)
For research purposes, semaglutide lyophilized powder is typically reconstituted using bacteriostatic water or sterile saline. Add reconstitution fluid slowly by directing it to the side of the vial and swirling gently — do not shake. Handle under sterile conditions and avoid repeated freeze-thaw cycles to maintain peptide integrity and potency. Protect reconstituted solution from direct light exposure.
Disclaimer
This product is sold for research and laboratory use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. Must be handled by qualified researchers in accordance with all applicable laws and regulations.