Ipamorelin 10mg
$34.99
Ipamorelin | 10mg | Research Peptide
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue (GHS) consisting of five amino acids — Aib-His-D-2-Nal-D-Phe-Lys-NH₂. It belongs to the ghrelin mimetic class of research compounds and functions by selectively binding to the growth hormone secretagogue receptor (GHSR-1a), stimulating the pulsatile release of growth hormone (GH) from the anterior pituitary gland. What distinguishes ipamorelin from earlier generation growth hormone secretagogues is its remarkable selectivity — it stimulates GH release without significantly elevating cortisol, prolactin, or ACTH levels, side effects commonly associated with less selective compounds in the same class.
First developed and studied in the late 1990s, ipamorelin was identified as one of the cleanest and most selective GHS peptides available for research purposes. Its highly targeted mechanism of action, combined with its favorable stability profile and predictable dose-dependent GH release, has made it a widely utilized tool across growth hormone biology, metabolic research, and aging studies. Preclinical research conducted primarily in rodent and porcine models has investigated its effects on GH pulsatility, IGF-1 regulation, body composition, bone density, and tissue repair mechanisms.
Overview
Ipamorelin is a selective fifth-generation growth hormone secretagogue that stimulates GH release through GHSR-1a receptor activation with minimal off-target hormonal effects. Its clean selectivity profile and consistent, dose-dependent action have made it one of the most studied GHS peptides in growth hormone biology, anti-aging research, and metabolic science.
Product Details
Peptide: Ipamorelin
Type: Growth Hormone Secretagogue (GHS) / Ghrelin Mimetic / Pentapeptide
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Molecular Formula: C₃₈H₄₉N₉O₅
Molecular Weight: 711.85 g/mol
CAS Number: 170851-70-4
Quantity: 10mg
Appearance: Lyophilized white powder
Purity: ≥99% (HPLC verified)
Reconstitution Fluid: Bacteriostatic Water (BW) or Sterile Saline (0.9% NaCl)
Storage: Store lyophilized peptide at -20°C. Upon reconstitution, store at 4°C and use within 30 days. Avoid repeated freeze-thaw cycles. Protect from light.
Research Applications
Ipamorelin has been extensively studied in preclinical models for its potential roles in:
Growth Hormone Secretion Research — Investigated for its selective and dose-dependent stimulation of pulsatile GH release via GHSR-1a receptor activation in pituitary tissue models, without significant elevation of cortisol, prolactin, or ACTH.
IGF-1 Regulation Studies — Studied for its downstream influence on insulin-like growth factor-1 (IGF-1) production in hepatic tissue, a key mediator of growth hormone's anabolic and regenerative effects.
Body Composition Research — Preclinical models have explored ipamorelin's potential to influence lean muscle mass preservation, fat metabolism, and overall body composition through GH-mediated pathways.
Bone Density Research — Studies in rodent models have examined ipamorelin's effects on bone mineral density and osteoblast activity, with particular interest in age-related bone loss models.
Tissue Repair & Recovery — Investigated for its role in accelerating tissue repair and collagen synthesis through GH and IGF-1 mediated anabolic signaling pathways.
Anti-Aging & Longevity Research — As GH secretion naturally declines with age, ipamorelin is studied as a research tool for investigating GH restoration strategies and their effects on age-related metabolic and physiological decline.
Sleep & Circadian Biology — Preclinical research has explored ipamorelin's influence on GH release during sleep cycles, given the natural correlation between deep sleep stages and peak GH pulsatility.
Research Notes
Ipamorelin is a research chemical intended strictly for laboratory and in vitro/in vivo research use only. It is not approved for human consumption, therapeutic use, or veterinary application. All data and findings referenced are sourced from peer-reviewed preclinical studies.
Handling & Reconstitution (For Research Use)
For research purposes, ipamorelin lyophilized powder is typically reconstituted using bacteriostatic water or sterile saline. Add reconstitution fluid slowly by directing it to the side of the vial and swirling gently — do not shake. Handle under sterile conditions and avoid repeated freeze-thaw cycles to maintain peptide integrity and potency. Protect reconstituted solution from direct light exposure.
Disclaimer
This product is sold for research and laboratory use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. Must be handled by qualified researchers in accordance with all applicable laws and regulations.