GHRP-2 10mg
$34.99
GHRP-2 | 10mg | Research Peptide
What is GHRP-2?
GHRP-2 (Growth Hormone Releasing Peptide-2), also known as Pralmorelin, is a synthetic hexapeptide and second-generation growth hormone secretagogue (GHS) consisting of six amino acids — D-Ala-D-βNal-Ala-Trp-D-Phe-Lys-NH₂. It belongs to the ghrelin mimetic class of research peptides and functions by selectively binding to the growth hormone secretagogue receptor (GHSR-1a) in the pituitary gland and hypothalamus, triggering a robust and dose-dependent release of endogenous growth hormone (GH). As a second-generation GHS compound, GHRP-2 represents a significant advancement over its predecessor GHRP-6, offering a stronger GH release response while producing comparatively fewer off-target effects related to appetite stimulation.
GHRP-2 has been studied extensively since the early 1990s and remains one of the most well-characterized growth hormone secretagogues in peptide research. Its potent stimulation of GH release, combined with a well-documented ability to amplify GH pulses when co-administered with growth hormone releasing hormone (GHRH) analogs, has made it a cornerstone compound in GH biology research. Beyond its primary mechanism of GH secretion, preclinical studies have also investigated GHRP-2's influence on IGF-1 regulation, appetite and energy homeostasis via ghrelin receptor signaling, cytoprotective pathways, and its potential anti-inflammatory properties. Its consistent performance across a wide range of in vitro and in vivo research models has established GHRP-2 as one of the most versatile and reliable tools available in growth hormone and metabolic research.
Overview
GHRP-2 is a potent second-generation synthetic growth hormone secretagogue that stimulates robust GH release through selective GHSR-1a receptor activation in the pituitary and hypothalamus. With one of the strongest GH stimulation profiles among GHS peptides and a well-established synergistic relationship with GHRH analogs, GHRP-2 has become a foundational research tool in growth hormone biology, metabolic science, and anti-aging research.
Product Details
Peptide: GHRP-2 (Pralmorelin)
Type: Growth Hormone Releasing Peptide / Growth Hormone Secretagogue (GHS) / Hexapeptide
Sequence: D-Ala-D-βNal-Ala-Trp-D-Phe-Lys-NH₂
Molecular Formula: C₄₅H₅₅N₉O₆
Molecular Weight: 817.99 g/mol
CAS Number: 158861-67-7
Quantity: 10mg
Appearance: Lyophilized white powder
Purity: ≥99% (HPLC verified)
Reconstitution Fluid: Bacteriostatic Water (BW) or Sterile Saline (0.9% NaCl)
Storage: Store lyophilized peptide at -20°C. Upon reconstitution, store at 4°C and use within 30 days. Avoid repeated freeze-thaw cycles. Protect from light.
Research Applications
GHRP-2 has been extensively studied in preclinical models for its potential roles in:
Growth Hormone Secretion Research — Investigated for its potent and dose-dependent stimulation of pulsatile GH release via GHSR-1a receptor activation in anterior pituitary tissue models, with one of the strongest GH release profiles among GHS peptides.
GHRH Synergy Studies — Studied extensively for its synergistic amplification of GH release when co-administered with growth hormone releasing hormone (GHRH) analogs such as CJC-1295, producing significantly greater GH output than either compound alone.
IGF-1 Regulation Research — Investigated for its downstream influence on insulin-like growth factor-1 (IGF-1) production in hepatic tissue models, a primary mediator of GH's anabolic, regenerative, and metabolic effects.
Body Composition Research — Preclinical models have explored GHRP-2's potential to influence lean muscle preservation, lipolysis, and overall body composition through GH and IGF-1 mediated signaling pathways.
Appetite & Energy Homeostasis Research — As a ghrelin mimetic, GHRP-2 has been studied for its activation of ghrelin receptors and downstream effects on appetite regulation, energy balance, and gastric motility in animal models.
Cytoprotective Research — Preclinical studies have investigated GHRP-2's potential cytoprotective properties, particularly in cardiac and hepatic tissue models subjected to ischemic or oxidative stress conditions.
Anti-Inflammatory Research — Studied for its potential to modulate inflammatory cytokine expression and reduce systemic inflammatory markers in in vivo research models.
Anti-Aging & Longevity Research — As endogenous GH secretion declines with advancing age, GHRP-2 is widely used as a research tool for investigating GH restoration strategies and their effects on age-related metabolic, musculoskeletal, and physiological decline.
Bone Density Research — Studies have examined GHRP-2's influence on bone mineral density and osteoblast activity through GH and IGF-1 mediated pathways in preclinical aging models.
Research Notes
GHRP-2 is a research chemical intended strictly for laboratory and in vitro/in vivo research use only. It is not approved for human consumption, therapeutic use, or veterinary application. All data and findings referenced are sourced from peer-reviewed preclinical studies.
Handling & Reconstitution (For Research Use)
For research purposes, GHRP-2 lyophilized powder is typically reconstituted using bacteriostatic water or sterile saline. Add reconstitution fluid slowly by directing it to the side of the vial and swirling gently — do not shake. Handle under sterile conditions and avoid repeated freeze-thaw cycles to maintain peptide integrity and potency. Protect reconstituted solution from direct light exposure.
Disclaimer
This product is sold for research and laboratory use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. Must be handled by qualified researchers in accordance with all applicable laws and regulations.