5-Amino-1MQ 10mg
$44.99
5-Amino-1MQ | 10mg | Research Compound
What is 5-Amino-1MQ?
5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small molecule research compound and selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme found primarily in fat tissue and the liver. NNMT plays a significant role in cellular energy metabolism by regulating the availability of SAM (S-adenosylmethionine) and NAD⁺ precursors — two molecules central to metabolic function and cellular energy balance.
By selectively blocking NNMT activity, 5-Amino-1MQ has drawn considerable attention in metabolic research. Preclinical studies conducted in rodent models have investigated its potential to influence fat cell differentiation, energy expenditure, and body composition without significant off-target effects. Its small molecular size allows it to penetrate cell membranes efficiently, making it a highly practical compound for in vitro and in vivo research applications.
Overview
5-Amino-1MQ is a selective NNMT inhibitor that has emerged as a prominent research compound in the fields of metabolic biology, obesity research, and cellular energetics. By modulating NNMT activity, it influences downstream NAD⁺ metabolism and methylation pathways, making it a valuable tool for researchers studying fat tissue biology and metabolic disease.
Product Details
Compound: 5-Amino-1-methylquinolinium (5-Amino-1MQ)
Molecular Formula: C₁₀H₁₀N₂
Molecular Weight: 158.20 g/mol
CAS Number: 54107-67-4
Quantity: 10mg
Appearance: Lyophilized powder
Purity: ≥99% (HPLC verified)
Reconstitution Fluid: Bacteriostatic Water (BW) or DMSO (dimethyl sulfoxide)
Storage: Store lyophilized compound at -20°C. Upon reconstitution, store at 4°C and protect from light. Use within 30 days.
Research Applications
5-Amino-1MQ has been studied in preclinical models for its potential roles in:
Metabolic Research — Investigated as a selective NNMT inhibitor with potential to influence fat cell (adipocyte) differentiation and metabolic rate in animal models.
Obesity & Body Composition Studies — Preclinical rodent studies have explored its role in reducing fat mass and influencing energy expenditure without dietary changes.
NAD⁺ Pathway Research — Studied for its effects on NAD⁺ availability and SAM metabolism, both of which are critical regulators of cellular energy and aging pathways.
Adipose Tissue Biology — Research has examined its influence on white adipose tissue browning and thermogenic gene expression.
Longevity & Aging Research — As NNMT activity is implicated in metabolic aging, 5-Amino-1MQ is being explored in the context of healthspan and age-related metabolic decline.
Research Notes
5-Amino-1MQ is a research chemical intended strictly for laboratory and in vitro/in vivo research use only. It is not approved for human consumption, therapeutic use, or veterinary application. All data and findings referenced are sourced from peer-reviewed preclinical studies.
Handling & Reconstitution (For Research Use)
For research purposes, 5-Amino-1MQ lyophilized powder is typically reconstituted using bacteriostatic water or DMSO depending on the assay requirements. Handle under sterile conditions. Avoid repeated freeze-thaw cycles to preserve compound integrity.
Disclaimer
This product is sold for research and laboratory use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. Must be handled by qualified researchers in accordance with all applicable laws and regulations.