KPV 10mg
$39.99
KPV | 10mg | Research Peptide
What is KPV?
KPV is a naturally occurring tripeptide consisting of three amino acids — Lysine (K), Proline (P), and Valine (V) — derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH). As a fragment of α-MSH, KPV retains many of the parent hormone's key biological properties, particularly its well-documented anti-inflammatory activity, while being significantly smaller in molecular size. This compact structure allows KPV to interact efficiently with intracellular targets and cross biological barriers that larger peptides cannot.
First studied in the context of melanocortin receptor signaling, KPV has since attracted broad research interest across multiple disciplines including gastroenterology, immunology, and dermatology. Its ability to modulate inflammatory pathways at both the cellular and systemic level — without the hormonal activity associated with the full α-MSH sequence — has made it a highly targeted and versatile research compound. Preclinical studies have primarily been conducted in rodent models, with particular focus on gut inflammation, wound healing, and immune regulation.
Overview
KPV is a tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH) that has emerged as a prominent anti-inflammatory research compound. By interacting with melanocortin receptors and intracellular inflammatory signaling pathways, KPV has become a valuable tool for researchers studying inflammatory bowel conditions, skin barrier function, and immune modulation.
Product Details
Peptide: KPV (Lys-Pro-Val)
Type: Tripeptide / α-MSH Fragment
Molecular Formula: C₁₆H₃₀N₄O₄
Molecular Weight: 342.44 g/mol
CAS Number: 69679-67-0
Quantity: 10mg
Appearance: Lyophilized white powder
Purity: ≥99% (HPLC verified)
Reconstitution Fluid: Bacteriostatic Water (BW) or Sterile Saline (0.9% NaCl)
Storage: Store lyophilized peptide at -20°C. Upon reconstitution, store at 4°C and use within 30 days. Avoid repeated freeze-thaw cycles.
Research Applications
KPV has been extensively studied in preclinical models for its potential roles in:
Anti-Inflammatory Research — Investigated for its ability to suppress pro-inflammatory cytokines including IL-6, IL-8, and TNF-α in both in vitro and in vivo models.
Gastrointestinal Research — Preclinical studies have explored KPV's potential to reduce intestinal inflammation and support gut barrier integrity, with particular focus on colitis models.
Dermatological Research — Studied for its role in skin inflammation modulation, wound healing acceleration, and barrier repair in epidermal tissue models.
Immune Modulation — Research has examined KPV's interaction with melanocortin receptors on immune cells, and its downstream effects on macrophage and T-cell activity.
Melanocortin Receptor Studies — As a direct fragment of α-MSH, KPV is used as a research tool to study MC1R and MC3R receptor signaling pathways involved in inflammation and immune response.
Research Notes
KPV is a research chemical intended strictly for laboratory and in vitro/in vivo research use only. It is not approved for human consumption, therapeutic use, or veterinary application. All data and findings referenced are sourced from peer-reviewed preclinical studies.
Handling & Reconstitution (For Research Use)
For research purposes, KPV lyophilized powder is typically reconstituted using bacteriostatic water or sterile saline. Add reconstitution fluid slowly by directing it to the side of the vial and swirling gently — do not shake. Handle under sterile conditions and avoid repeated freeze-thaw cycles to maintain peptide integrity and potency.
Disclaimer
This product is sold for research and laboratory use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. Must be handled by qualified researchers in accordance with all applicable laws and regulations.